Start your primary DTaP immunization series in children 6 weeks through 4 years of age (prior to 5th birthday) with 4 doses of Pentacel, the only DTaP-IPVb-Hibc combination. Finish the DTaP series with Quadracel as the 5th dose in children 4 through 6 years of age.1,2
Completing the series with Pentacel and Quadracel reduces the number of injections as compared with single-entity vaccines. By using Quadracel, it satisfies the ACIP’sd 5-dose DTaP recommendation with full antigen continuity.1-4
Pentacel is indicated for active immunization against diphtheria, tetanus, pertussis, poliomyelitis, and invasive disease due to H influenzae type b. Pentacel is approved for use as a 4-dose series in children 6 weeks through 4 years of age (prior to fifth birthday).
Quadracel is indicated for active immunization against diphtheria, tetanus, pertussis, and poliomyelitis. A single dose of Quadracel is approved for use in children 4 through 6 years of age as a fifth dose in the diphtheria, tetanus, pertussis vaccination (DTaP) series, and as a fourth or fifth dose in the inactivated poliovirus vaccination (IPV) series, in children who have received 4 doses of Pentacel vaccine and/or DAPTACEL® (Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed).
The only Hib-containing DTaP-IPV
combination vaccine with a
4-dose indication1
The same liquid DTaP-IPV component as
in Pentacel1,2
Antigens
DTaP-IPV/Hib1
DTaP-IPV2
Schedule
Doses at 2, 4, 6, and 15-18 months1,3
A dose at 4-6 years2,3
Birth Birth |
1 Month 1 Mo. |
2 Months 2 Mos. |
4 Months 4 Mos. |
6 Months 6 Mos. |
12 Months 12 Mos. |
15 Months 15 Mos. |
18 Months 18 Mos. |
19-23 Months 19-23 Mos. |
2-3 Years 2-3 Yrs. |
4-6 Years 4-6 Yrs. |
---|---|---|---|---|---|---|---|---|---|---|
Hep B | Hep B | Hep B | ||||||||
DTaP | DTaP | DTaP | DTaP | DTaP | ||||||
IPV | IPV | IPV | IPV | |||||||
Hib | Hib | Hib | Hib | Hib | ||||||
RV | RV | RVe | ||||||||
PCV | PCV | PCV | PCV | PCV | ||||||
Influenza (yearly) | ||||||||||
MMRf | MMR | MMR | ||||||||
Varicella | Varicella | |||||||||
Hep A (2-dose series) | Hep A (2-dose series) | |||||||||
MenACWY | ||||||||||
PPSV | ||||||||||
Birth Birth |
1 Month 1 Mo. |
2 Months 2 Mos. |
4 Months 4 Mos. |
6 Months 6 Mos. |
12 Months 12 Mos. |
15 Months 15 Mos. |
18 Months 18 Mos. |
19-23 Months 19-23 Mos. |
2-3 Years 2-3 Yrs. |
4-6 Years 4-6 Yrs. |
---|---|---|---|---|---|---|---|---|---|---|
Hep B | Hep B | Hep B | ||||||||
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||||||||
Hib | ||||||||||
RV | RV | RVe | ||||||||
PCV | PCV | PCV | PCV | PCV | ||||||
Influenza (yearly) | ||||||||||
MMRf | MMR | MMR | ||||||||
Varicella | Varicella | |||||||||
Hep A (2-dose series) | Hep A (2-dose series) | |||||||||
MenACWY | ||||||||||
PPSV | ||||||||||
Birth Birth |
1 Month 1 Mo. |
2 Months 2 Mos. |
4 Months 4 Mos. |
6 Months 6 Mos. |
12 Months 12 Mos. |
15 Months 15 Mos. |
18 Months 18 Mos. |
19-23 Months 19-23 Mos. |
2-3 Years 2-3 Yrs. |
4-6 Years 4-6 Yrs. |
---|---|---|---|---|---|---|---|---|---|---|
Hep B | Hep B | Hep B | ||||||||
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||||||||
Hib | ||||||||||
RV | RV | RVe | ||||||||
PCV | PCV | PCV | PCV | PCV | ||||||
Influenza (yearly) | ||||||||||
MMRf | MMR | MMR | ||||||||
Varicella | Varicella | |||||||||
Hep A (2-dose series) | Hep A (2-dose series) | |||||||||
MenACWY | ||||||||||
PPSV | ||||||||||
Contraindications to vaccination with Pentacel or Quadracel vaccine include: a severe allergic reaction (e.g., anaphylaxis) to any ingredient of the vaccine, or following any other diphtheria toxoid-, tetanus toxoid-, pertussis antigen-containing vaccine, inactivated poliovirus vaccine, or Haemophilus influenzae type b vaccine (Pentacel only); encephalopathy within 7 days after a previous dose of a pertussis antigen-containing vaccine with no other identifiable cause; or a progressive neurologic disorder.
Please see full Prescribing Information for Pentacel (49281-0510-05 and 49281-0511-05).