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For US Health Care Professionals

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Pentacel® mascot dressed as a doctor

HELPING PROTECT KIDS IS A FULL-TIME JOB AND PENTACEL IS UP TO THE TASK

Let’s work together and help protect kids against potentially deadly diseases with the DTaP-IPV/Hib vaccine.1

INDICATION FOR PENTACEL

Pentacel is a vaccine indicated for active immunization against diphtheria, tetanus, pertussis, poliomyelitis, and invasive disease due to Haemophilus influenzae type b. Pentacel is approved for use as a 4-dose series in children 6 weeks through 4 years of age (prior to 5th birthday).

START WITH PENTACEL

Start your primary DTaP immunization series in children 6 weeks through 4 years of age (prior to 5th birthday) with 4 doses of Pentacel, the only DTaP-IPV-Hib combination vaccine.1

Pentacel® mascot dressed as a doctor Pentacel® mascot dressed as a doctor

Even if you didn’t use Pentacel for the first 3 doses, you can use it for the fourth dose

of the DTaP series containing the same pertussis antigens as in Pentacel.1*

*Data are not available on the safety and effectiveness of using mixed sequences of Pentacel and DTaP vaccine from different manufacturers.

illustration of a kid dressed for scuba

Pentacel may simplify vaccine administration by supporting
A VACCINATION SCHEDULE
WITH FEWER INJECTIONS
compared to single-entity alternatives1-3

Centers for Disease Control and Prevention schedule through 6 years of age2
IMPACT OF PENTACEL1
POTENTIAL SHOT
SAVINGS1
WITHOUT PENTACEL1
Vaccine Down arrow Age Down arrow
Hepatitis B Hep B
Diphtheria, tetanus, pertussis DTaP
Inactivated poliovirus Polio
Haemophilus influenzae type b Hib
Rotavirus RV
Pneumococcal conjugate PCV
Influenza (2 doses for some) Flu (2 doses for some)
Measles, mumps, rubella MMR
Varicella Varicella
Hepatitis A Hep A
Meningococcal MenACWY
Pneumococcal polysaccharide PPSV

Birth
Birth
1
Month
1
Mo.
2
Months
2
Mos.
4
Months
4
Mos.
6
Months
6
Mos.
9
Months
9
Mos.
12
Months
12
Mos.
15
Months
15
Mos.
18
Months
18
Mos.
19-23
Months
19-23
Mos.
2-3
Years
2-3
Yrs.
4-6
Years
4-6
Yrs.
Hep B Hep B Hep B
DTaP DTaP DTaP DTaP DTaP
IPV IPV IPV IPV
Hib Hib Hib Hib Hib
RV RV RVb
PCV PCV PCV PCV PCV
Influenza (yearly)
MMRc MMR MMR
Varicella Varicella
Hep A Hep A (2-dose series)
MenACWY
PPSV

Birth
Birth
1
Month
1
Mo.
2
Months
2
Mos.
4
Months
4
Mos.
6
Months
6
Mos.
9
Months
9
Mos.
12
Months
12
Mos.
15
Months
15
Mos.
18
Months
18
Mos.
19-23
Months
19-23
Mos.
2-3
Years
2-3
Yrs.
4-6
Years
4-6
Yrs.
Hep B Hep B Hep B
DTaP IPV
Hib
RV RV RVb
PCV PCV PCV PCV PCV
Influenza (yearly)
MMRc MMR MMR
Varicella Varicella
Hep A Hep A (2-dose series)
MenACWY
PPSV

Birth
Birth
1
Month
1
Mo.
2
Months
2
Mos.
4
Months
4
Mos.
6
Months
6
Mos.
9
Months
9
Mos.
12
Months
12
Mos.
15
Months
15
Mos.
18
Months
18
Mos.
19-23
Months
19-23
Mos.
2-3
Years
2-3
Yrs.
4-6
Years
4-6
Yrs.
Hep B Hep B Hep B
DTaP IPV
Hib
RV RV RVb
PCV PCV PCV PCV PCV
Influenza (yearly)
MMRc MMR MMR
Varicella Varicella
Hep A Hep A (2-dose series)
MenACWY
PPSV
Illustration of handshake

Our journey and promise continue

Thank you for continuing to trust Pentacel for your primary DTaP immunization.1 We remain committed to helping you and your patients. Together, Sanofi’s promise to help protect stands strong.

Data that demonstrate protection

Know that with Pentacel, your patients’ protection is backed by data. Pentacel has been evaluated in 4 clinical trials, and safety was demonstrated consistently.1

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Approved by the FDA

Pentacel is the only FDA-approved, 4-dose DTaP combination vaccine.1,2

Your commitment to Pentacel gives
your patients access to complete the
recommended schedule.

Nationally, between 2019 and 2020, there was a drop-off of vaccination for the fourth dose of DTaP and Hib. The 13% drop-off for DTaP and 14% drop off for Hib could put patients at risk for disease5

Down arrow
bottle with number 4 on it

Even if you didn’t use Pentacel for the first 3 doses, you can use it for the 4th dose of the DTaP series, containing the same pertussis antigens as in Pentacel1*

*Data are not available on the safety and effectiveness of using mixed sequences of Pentacel and DTaP vaccine from different manufacturers.

Continuing to choose Pentacel for the 4th dose helps your patients receive the protection that Pentacel has to offer1,2,5

illustration of shield
illustration of hands

Parents and kids count on you. You can keep counting on us.

Important Safety Information for Pentacel

Contraindications to vaccination with Pentacel include: a severe allergic reaction (e.g., anaphylaxis) after a previous dose of Pentacel, or any other diphtheria toxoid-, tetanus toxoid-, pertussis antigen-containing vaccine, inactivated poliovirus vaccine, or Haemophilus influenzae type b vaccine, any ingredient of Pentacel; encephalopathy within 7 days after a previous dose of a pertussis antigen-containing vaccine with no other identifiable cause; or a progressive neurologic disorder.

Please see full Prescribing Information for Pentacel.
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Please see full Prescribing Information for Pentacel.
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Please see full Prescribing Information for Pentacel.
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