Let's work together and help protect kids against potentially deadly diseases with the DTaP-IPV/Hib vaccine.1
Pentacel is indicated for active immunization against diphtheria, tetanus, pertussis, poliomyelitis, and invasive disease due to H influenzae type b. Pentacel is approved for use as a 4-dose series in children 6 weeks through 4 years of age (prior to fifth birthday).
Quadracel is indicated for active immunization against diphtheria, tetanus, pertussis, and poliomyelitis. A single dose of Quadracel is approved as a fifth dose in the diphtheria, tetanus, pertussis (DTaP) vaccination series, and as a fourth or fifth dose in the inactivated poliovirus (IPV) vaccination series, in children 4 through 6 years of age whose previous DTaP vaccine doses have been with Pentacel and/or DAPTACEL® (Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed), and/or VAXELIS® (Diphtheria and Tetanus Toxoids and Acellular Pertussis, Inactivated Poliovirus, Haemophilus b Conjugate and Hepatitis B Vaccine).
Start your primary DTaP immunization series in children 6 weeks through 4 years of age (prior to 5th birthday) with 4 doses of Pentacel, the only DTaP-IPV-Hib combination.1
Finish the DTaP series with Quadracel as the 5th dose in children 4 through 6 years of age.2
The only Hib-containing DTaP-IPV
combination vaccine with a
4-dose indication1
The same liquid DTaP-IPV component as
in Pentacel1,2
Antigens
DTaP-IPV/Hib1
DTaP-IPV2
Schedule
Doses at 2, 4, 6, and 15-18 months1,3
A dose at 4-6 years2,3
*Data are not available on the safety and effectiveness of using mixed sequences of Pentacel and DTaP vaccine from different manufacturers.
Birth Birth |
1 Month 1 Mo. |
2 Months 2 Mos. |
4 Months 4 Mos. |
6 Months 6 Mos. |
9 Months 9 Mos. |
12 Months 12 Mos. |
15 Months 15 Mos. |
18 Months 18 Mos. |
19-23 Months 19-23 Mos. |
2-3 Years 2-3 Yrs. |
4-6 Years 4-6 Yrs. |
---|---|---|---|---|---|---|---|---|---|---|---|
Hep B | Hep B | Hep B | |||||||||
DTaP | DTaP | DTaP | DTaP | DTaP | |||||||
IPV | IPV | IPV | IPV | ||||||||
Hib | Hib | Hib | Hib | Hib | |||||||
RV | RV | RVb | |||||||||
PCV | PCV | PCV | PCV | PCV | |||||||
Influenza (yearly) | |||||||||||
MMRc | MMR | MMR | |||||||||
Varicella | Varicella | ||||||||||
Hep A | Hep A (2-dose series) | ||||||||||
MenACWY | |||||||||||
PPSV | |||||||||||
Birth Birth |
1 Month 1 Mo. |
2 Months 2 Mos. |
4 Months 4 Mos. |
6 Months 6 Mos. |
9 Months 9 Mos. |
12 Months 12 Mos. |
15 Months 15 Mos. |
18 Months 18 Mos. |
19-23 Months 19-23 Mos. |
2-3 Years 2-3 Yrs. |
4-6 Years 4-6 Yrs. |
---|---|---|---|---|---|---|---|---|---|---|---|
Hep B | Hep B | Hep B | |||||||||
Hib | |||||||||||
RV | RV | RVb | |||||||||
PCV | PCV | PCV | PCV | PCV | |||||||
Influenza (yearly) | |||||||||||
MMRc | MMR | MMR | |||||||||
Varicella | Varicella | ||||||||||
Hep A | Hep A (2-dose series) | ||||||||||
MenACWY | |||||||||||
PPSV | |||||||||||
Birth Birth |
1 Month 1 Mo. |
2 Months 2 Mos. |
4 Months 4 Mos. |
6 Months 6 Mos. |
9 Months 9 Mos. |
12 Months 12 Mos. |
15 Months 15 Mos. |
18 Months 18 Mos. |
19-23 Months 19-23 Mos. |
2-3 Years 2-3 Yrs. |
4-6 Years 4-6 Yrs. |
---|---|---|---|---|---|---|---|---|---|---|---|
Hep B | Hep B | Hep B | |||||||||
Hib | |||||||||||
RV | RV | RVb | |||||||||
PCV | PCV | PCV | PCV | PCV | |||||||
Influenza (yearly) | |||||||||||
MMRc | MMR | MMR | |||||||||
Varicella | Varicella | ||||||||||
Hep A | Hep A (2-dose series) | ||||||||||
MenACWY | |||||||||||
PPSV | |||||||||||
Contraindications to vaccination with Pentacel or Quadracel vaccine include: a severe allergic reaction (e.g., anaphylaxis) to any ingredient of the vaccine, or following any other diphtheria toxoid-, tetanus toxoid-, pertussis antigen-containing vaccine, inactivated poliovirus vaccine, or Haemophilus influenzae type b vaccine (Pentacel only); encephalopathy within 7 days after a previous dose of a pertussis antigen-containing vaccine with no other identifiable cause; or a progressive neurologic disorder.